Relationship between diverticulitis and colon cancer
Comparing right- and left-sided colon cancer
Diverticulosis and colorectal neoplasia have similar epidemiological patterns and risk factors, and their incidences rise with age in Western countries. However, the evidence for a correlation between diverticulosis and colorectal neoplasia is mixed. As a result, we conducted a meta-analysis to see whether diverticulosis is linked to colorectal neoplasia.
To find studies that looked at the connection between diverticulosis and advanced colorectal neoplasia (advanced adenoma, colorectal cancer), adenomas, or polyps, researchers searched PubMed, EMBASE, Cochrane Library, Web of Science, and SCOPUS. Patients’ demographic characteristics, such as age, gender, colonoscopy indication, confounding factors, and colorectal neoplasia outcomes, were analyzed.
The relation between diverticulosis and colorectal neoplasia was studied in 29 cross-sectional studies (N = 450,953). Diverticulosis was not linked to advanced colorectal neoplasia in the meta-analysis (odds ratio [OR] 0.98, 95 percent confidence interval [CI] 0.63–1.50). Diverticulosis did not raise the risk of adenomas (OR 1.34, 95 percent CI 0.87–2.06) in patients who underwent screening colonoscopy, despite a positive association between diverticulosis and adenomas (OR 1.47, 95 percent CI 1.18–1.84) and diverticulosis and polyps (OR 1.95, 95 percent CI 1.15–3.31). Furthermore, all of the increased risk of colorectal neoplasia in diverticulosis patients was found only in published research, not in unpublished ones.
Fiber: diverticulosis and colon cancer – dr. hans diehl
Many health-conscious individuals may recite their cholesterol, blood pressure, and PSA levels without ever consulting their medical records. Despite the fact that diverticular disease of the colon is a very common illness, few of these well-informed gentlemen will tell you whether they have it. That’s understandable, given that diverticulosis, the most common type of the problem, has little, if any, symptoms. When complications arise, however, blissful ignorance about diverticulosis gives way to an unexpected lesson about diverticulitis pain or diverticulosis bleeding. It’s an especially unfortunate learning experience, since diverticular disease is largely preventable.
The colon is a 4 1/2-foot-long conduit that connects the upper and lower intestines. The stomach and small intestine digest the most of the food you consume. The cecum, which is situated in the right lower portion of the abdomen, is where leftover material reaches the colon, or large intestine (see Figure 1). The digested material then moves up the ascending colon, through the transverse colon, and down the descending colon to the sigmoid colon, which is situated in the lower left abdomen. The intestinal contents pass through the colon in around 18 to 36 hours, with the few remaining nutrients snatched into the bloodstream and most of the water consumed, resulting in solid feces. The colon is a smooth cylinder lined by epithelial cells when it is healthy. Two groups of muscles line the colon’s wall: a circular muscle that surrounds the colon and three long muscles that run the length of the tunnel. The colon, like all tissues, needs a supply of blood, which is supplied in part by the numerous small penetrating arteries that pass through the colon’s muscular wall to transport blood to the epithelial cells that make up its inner layer.
Diverticular disease (diverticulitis) – overview
According to a systematic review and meta-analysis published in Clinical Gastroenterology and Hepatology, patients with complicated diverticulitis are six times more likely to develop colorectal cancer than patients with uncomplicated diverticulitis.
Although some experts suggest regular colonoscopy for all patients with diverticulitis, the procedure has been debated due to the suspected disparity in risk for CRC, according to PhD, of the division of digestive and transplantation surgery at University Hospitals of Geneva in Switzerland, and colleagues.
“In order to determine whether or not these patients will benefit from diagnostic endoscopy, robust data estimating the prevalence of [CRC] in patients initially diagnosed with diverticulitis are needed,” they wrote. “Colonoscopy is an expensive procedure that can result in potentially fatal complications, so it should only be used in patients that have a high risk of [CRC].”
CRC was found to be prevalent in 1.9 percent of the population (95 percent confidence interval: 1.5 percent–2.3 percent). Polyps (22.7 percent ; 95 percent CI, 19.6 percent –26 percent ), advanced adenomas (4.4 percent ; 95 percent CI, 3.4 percent –5.8 percent ), adenomas (14.2 percent ; 95 percent CI, 11.7 percent –17.1 percent ), and hyperplastic polyps (9.2 percent ; 95 percent CI, 7.6 percent –11.2 percent ) were all present in patients that had a colonoscopy
What is diverticulitis / diverticulosis? a colorectal surgeon
Hello, could someone please assist me? I’m in a lot of pain. I was concerned that I may have ovarian cancer due to the following symptoms: severe left abdominal pain, chronic lower backache, pain in groin and down left leg, fever and chills, extreme exhaustion to the point of dragging myself through the day, constipation, regular and urgent need to urinate, and now nausea. There is a lump that induces a lot of tenderness and bloating. My GP ordered a pap smear, pelvic ultrasound, and CA 125 blood test, all of which came back negative, but my white blood cell count has risen on blood tests. I went to the hospital last week, and the doctor said he doesn’t believe it’s a gynecological problem, but he’s pretty sure it’s all about the colon. On second thought, this makes sense. I’m in so much pain right now that I don’t know what to do; all I can do is wait for the cat scan appointment that he’s scheduled for me. Meanwhile, I’m terrified because it’s getting worse and I’m not sure whether it’s colon cancer or Diverticular disease. Is someone encountered any or all of these symptoms? Any suggestions you can give me will be greatly appreciated. I’m at the point that I’m worried I’ll pass out and have to go to the hospital because the doctors have been avoiding me for too long before I actually pushed them enough to get me this far. Thank you all so much!