Chronic pancreatitis prognosis and life expectancy
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A scientifically based definition of chronic pancreatitis is proposed. Chronic pancreatitis is a condition that affects the pancreas (diagnosis) At least one clinical criteria (Table 1), such as pain, (recurrent) acute pancreatitis attacks, steatorrhea, diabetes mellitus, or well-defined chronic pancreatitis complications (Table 2), is required for the diagnosis of chronic pancreatitis. These clinical criteria must be followed by well-defined imaging anomalies (Table 3) or a direct pancreatic function examination. Table 1 shows the clinical criteria. Panel that is full size
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Eighty-two chronic pancreatitis patients were monitored for an average of 25 months (median 25 months). Before being included in this report, none of them had received an endoscopic treatment. The patients were 48 years old on average (range 29 to 78, median 49), with a 6.5:1 male:female ratio. In 84.2 percent of cases, the cause was alcoholic, in 8.5 percent, it was pancreas divisum, and in 7.3 percent of cases, it was idiopathic.
The mortality rate was 17% during the follow-up period, with death occurring on average 59 months (median 53 months) after the onset of the disease. Pancreatic cancer (3.6 percent), surgical complications (3.6 percent), and upper digestive hemorrhage were the leading causes of death (2.4 percent ). Diabetes, no improvement in pain after surgery, and continued smoking were all risk factors for death. The form of medication used had little bearing on survival. At three years, the average survival rate was calculated to be 80 percent, and at five years, it was 59 percent.
The mortality rate for chronic pancreatitis was higher than previously estimated. Pancreatic cancer claimed the lives of 3.6 percent of the patients. Extra pancreatic cancers did not result in any deaths. The prevalence of diabetes, continued smoking, and no relief from pain under care were all risk factors for death.
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The pain typically starts in the middle or left side of your abdomen, but it can also move up your spine. It’s characterized as a burning or shooting pain that comes and goes, but can sometimes last for several hours or days.
Between episodes of extreme pain, a persistent mild to moderate pain in the abdomen may develop. People who continue to drink alcohol after being diagnosed with chronic pancreatitis are more likely to develop this condition.
When the pancreas loses its ability to produce digestive juices, which aid in the digestion of food, additional symptoms may arise. These functions of the pancreas are normally lost several years after the initial symptoms appear.
It’s difficult for your digestive system to break down fats and some proteins without digestive juices. This can make the stools smelly and greasy, as well as making them difficult to flush down the toilet.
If you develop signs of jaundice, you should also see your doctor. Other than pancreatitis, jaundice can be caused by a variety of things, but it’s typically a warning that something is wrong with your digestive system.
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Chronic pancreatitis may shorten life expectancy compared to people who do not have the disease; research has found that 10-year survival after diagnosis is up to 30% lower than in the general population. The mortality rate is about 10% if pancreatitis becomes acute. When acute pancreatitis is serious and includes injury, bleeding, or inflammation that has spread to other organs, the risk of death can be as high as 30%. Milder cases of acute pancreatitis, on the other hand, often recover completely with no impact on life expectancy.
Acute pancreatitis is a condition that affects the pancreas.
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