Can you take advil and zyrtec together
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Many people are aware that taking a sedative and an antihistamine at the same time will result in severe drowsiness, and that taking an anti-inflammatory such as Advil®, Aleve®, or Motrin® while taking a blood thinner increases the risk of hemorrhaging. However, some members of the medical community and the general public are unaware that traditional medicines can reduce the efficacy of some oral chemotherapy drugs (taken as liquids or pills) or cause toxic reactions in the body. These potentially fatal interactions are most often associated with liquid or pill chemotherapies, a drug class that has exploded in popularity since 2014, accounting for 25% of the 400 or so chemotherapy drugs in development. According to Anthony Perre, MD, Director of the Division of Outpatient Medicine at Cancer Treatment Centers of America®, “With the introduction of precision medicine, the vast majority of chemotherapy agents in the future will be oral” (CTCA). “In the past, a patient had to be admitted to the hospital for IV chemotherapy, and medication reactions were a big concern for everybody. These oral chemotherapies can now be taken at home by patients. Oral prescriptions may not have a fail-safe system, particularly if the patient lives in a rural area and visits a doctor who does not use electronic records. It’s possible that a pharmacist or a family doctor is unaware of the risks.”
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The first is anti-inflammatory, and the second is antihistamine. If you were taking Advil and then Aleve or whatever, that would be different. Isn’t it true that anti-inflammatories and antihistamines are often mixed in over-the-counter medications?
Yes, I’ve put them together more than once and come out alive. Have you tried Zyrtec to treat your hives? Only a few minutes ago, I had to take one because I went outside with my wrists exposed. Within 30 minutes, the itching and mild swelling that had begun had subsided.
I’m not sure why you can’t take Advil and Benadryl at the same time. The first is an anti-inflammatory, and the second is an antihistamine. To treat both allergy and concomitant headache, I’ve taken aspirin and antihistamine together.
Yes, Zyrtec is a better antihistamine for hives. Zyrtec is the only OTC that is explicitly for hives, according to my PA. Since I started taking Zyrtec, I haven’t had any hives severe enough to include a trip to the ER.
Ask the pharmacist – episode 15
Do you take several medications? Are you taking a variety of different medications? Are you seeing a variety of doctors? If that’s the case, you’re more likely to experience drug interactions, which arise when a drug, supplement, or even food alters how the body absorbs a medicine. Such interactions can make a medication more powerful—to the point that a normal dose becomes an overdose—or they can make it less potent or ineffective altogether.
The word “drug reactions” is a little deceptive. In the body, drugs do not interact to cause chemical reactions. Instead, a drug, supplement, or food may affect the length of time a medication stays in the body by stimulating or inhibiting the development of specific enzymes in the liver or intestine. The cytochrome p450 system, which is involved in the metabolization of several drugs, incorporates these enzymes. Drug reactions are most often caused by one of the following factors:
Interactions with other medicines are possible. When one drug affects the cytochrome enzyme that processes the other, an interaction occurs. The antibiotic metronidazole (Flagyl), for example, inhibits the CYP2C enzyme, which breaks down warfarin (Coumadin). The blood thinner will remain in the body if the two drugs are taken together, raising the risk of serious bleeding. Excess development of CYP3A4, the enzyme that metabolizes estradiol, a portion of low-dose contraceptives, is stimulated by the anti-seizure medication phenytoin (Dilantin). In this situation, the contraceptives are cleared more easily in women who are taking phenytoin, decreasing their efficacy and increasing the risk of an accidental pregnancy.
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The form of drug has an effect on the interactions. To understand how your prescription can interact with other medications, talk with your doctor or pharmacist and read the drug information that comes with it.