Can i take aspirin with lisinopril
How do ace inhibitors work?
If you’re pregnant, don’t use it, and if you get pregnant, call the doctor right away. If you take lisinopril during your second or third trimester, you risk harming or killing your unborn child.
If you’re sick with vomiting or diarrhea, or if you’re sweating more than normal, call your doctor. When taking lisinopril, you can quickly become dehydrated. This can result in dangerously low blood pressure, electrolyte imbalances, and kidney failure.
If you have hives, extreme stomach pain, trouble breathing, or swelling of your ears, mouth, tongue, or throat, seek immediate medical attention. If you’re African-American, you’re more likely to have an allergic reaction.
This is not an exhaustive list. Other drugs, such as prescription and over-the-counter medications, vitamins, and herbal products, can interact with lisinopril. This list does not include all potential drug reactions.
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It’s debatable if aspirin (ASA) has a clinical impact in patients taking angiotensin-converting enzyme (ACE) inhibitors. Several studies have indicated that ASA reduces the beneficial effects of ACE inhibitors in hypertension, congestive heart failure (CHF), and coronary artery disease (CAD), raising concerns about the safety of taking these drugs together. The aim of this research is to see if there is any interaction between ASA and an ACE inhibitor in hypertensive rats. Adult male Wistar rats were given 20 mg/kg of Methylprednisolone (MP) per week s.c. for two weeks to induce hypertension. The systolic blood pressure (SBP) was determined using a noninvasive blood pressure (BP) procedure. On hypertension caused by glucocorticoids, the effects of Lisinopril (LS) 15 mg/kg per day and a combination of LS and ASA; 100 and 25 mg/kg per day p.o. were investigated. The hypotensive effect of LS was unaffected by concurrent ASA treatment at either dose. ASA 100 mg/kg per day, on the other hand, caused death in animals and resulted in massive cardiac necrosis and renal damage, as evidenced by histopathology. Lower mortality was achieved with ASA 25 mg/kg per day treatment, which had varying effects on cardiac and renal tissues. These findings suggest that ASA reduces the beneficial effects of an ACE inhibitor on survival in hypertensive rats, with the effect being stronger at higher ASA doses.
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The relationship between aspirin and lisinopril has a Lexi-comp rating of C (on a scale of A-D, with X being contraindicated). I’d like your opinion on whether this conversation should be faxed to a doctor.
1. This patient was a long-term care facility resident. The hospital will provide a lot of knowledge about this resident’s blood pressure readings. The person who was prompted to engage in this conversation could easily pick up the phone and ask about the blood pressure readings with the nursing staff. When it comes to drug interactions, monitoring is critical, and this choice seems to fall through the cracks every now and then, as I’ve seen some providers panic and not care about what the warning is actually saying.
2. The second option is to ask the provider to evaluate the existing aspirin dosage. When the daily dose of aspirin is less than 100 mg, according to Lexicomp, this association does not occur or has a minor effect. In certain cases, an 81 mg daily dose is appropriate.
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The Portuguese Journal of Cardiology, the official journal of the Portuguese Society of Cardiology, was founded in 1982 with the aim of keeping Portuguese cardiologists informed by publishing scientific articles on topics such as arrhythmology and electrophysiology, cardiovascular surgery, intensive care, coronary artery disease, cardiovascular imaging, hypertension, heart failure, and vascular disease. The Journal is a monthly publication that adheres to high scientific content and performance requirements. It has been published in both English and Portuguese since 1999, which has increased its international readership. It is sent to all members of the Portuguese Societies of Cardiology, Internal Medicine, Pneumology, and Cardiothoracic Surgery, as well as leading non-Portuguese cardiologists and nearly all cardiology societies around the world. Since 1987, it has been referred to Medline.